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Питання №: 41What covalent modification is used mainly for regulation of enzyme activity? carboxylation methylation amination phosphorylation acetylation Питання №: 42To prevent attacks of acute pancreatitis a doctor prescribed the patient trasylol (contrycal, gordox), which is an inhibitor of: Trypsin Elastase Carboxypeptidase Pepsin Gastricsin Питання №: 43Only one factor can influence the charge of amino acid radicals in the active centre of enzyme. Name this factor: The presence of a competitive inhibitor The surplus of a product pH medium Pressure Temperature Питання №: 44How glucocorticoides influence the carbohydrates exchange? Stimulate the glycogenesis from glucose Stimulate the gluconeogenesis Stimulate the starch hydrolysis in the intestine Stimulate the glycogen phosphorolysis Stimulate the glycolysis Питання №: 45Metabolic conversion of pyruvic acid (pyruvate) to glucose is called: glycogenolysis glycolysis lipolysis glycogenesis gluconeogenesis Питання №: 46A newborn child was found to have reduced intensity of sucking, frequent vomiting, hypotonia. Urine and blood exhibit increased concentration of citrulline. What metabolic process is disturbed? Glyconeogenesis Cori cycle Tricarboxylic acid cycle Glycolysis Ornithinic cycle Питання №: 47A 4 y.o. boy has had recently serious viral hepatitis. Now there are such clinical presentations as vomiting, loss of consciousness, convulsions. Blood analysis revealed hyperammoniemia. Disturbunce of which biochemical process caused such pathological condition of the patient? Disturbed neutralization of ammonia in liver Disturbed neutralization of biogenic amines Increased putrefaction of proteins in bowels Activation of aminoacid decarboxylation Inhibition of transamination enzyms Питання №: 48The protective function of human saliva is realized in some ways, including the presence of an enzyme which shows bactericidal action accomplished by the lysis of membrane polysaccharides complexes of staphylococci and streptococci. Choose this enzyme from the following: Collagenase Amylase Oligo[1,6]-glucosidase Lysozyme beta-Glucuronidase Питання №: 49Untrained people often have muscle pain after sprints as a result of lactate accumulation. This might be caused by intensification of the following biochemical process: Lipogenesis Glycogenesis Pentose phosphate pathway Glycolysis Gluconeogenesis Питання №: 50Biosynthesis of the purine ring occurs owing to ribose-5-phosphate by gradual joining of nitrogen and carbon atoms inside the heterocyclic structure and closing of the rings. The metabolic source of ribose-5-phosphate is: Pentose phosphate pathway Glycolysis Glycogenesis Gluconeogenesis Glycogenosis Питання №: 51Patient with abscess of the cut wound applied to the traumatology department. Doctor for the cleaning of the wound from the pus washed it with 3% hydrogen peroxide. Foam was absence. What caused the absents on the drug activity? Inherited insufficiency of catalase Low concentration of H2O2 Inherited insufficiency phosphatedehydrogenase of erythrocytes Shallow wound Pus in the wound Питання №: 52A 42-year man suffering from gout has increased level of uric acid in the blood. Allopurinol was prescribed to decrease the level of uric acid. Competitive inhibitor of what enzyme is allopurinol? Xanthinoxidase Adenosinedeaminase Adeninephosphoribosiltransferase Hypoxantinphosphoribosiltransferase Guaninedeaminase Питання №: 53Which enzyme hydrolyzes carbohydrates in the mouth? Lactase alpa-Amylase Sucrase Maltase Lipase Питання №: 54The elevated activity of creatin phosphokinase (MM-form) in the blood is indication of: hepatitis muscle dystrophy acute pancreatitis kidney disease stomach disease Питання №: 55According to clinical indications a patient was administered pyridoxal phosphate. What processes is this medication intended to correct? Transamination and decarboxylation of amino acids Oxidative decarboxylation of ketonic acids Desamination of purine nucleotides Synthesis of purine and pyrimidine bases Protein synthesis Питання №: 56A child is sluggish and inert. His liver is enlarged. The liver biopsy showed the excess of glycogen. The concentration of glucose in blood plasma is below the normal range. What is the cause of the glucose level decrease in blood? High activity of glycogen phosphorylase in the liver Reduced (or absent) activity of hexokinase High activity of glycogen synthase Reduced (or absent) activity of glucose-6-phosphatase Deficiency of the gene, which is responsible for the synthesis of glucose-1-phosphate uridine transferase Питання №: 57During the necropsy of a 20-year-old girl a pathologist discovered that her death had resulted from poisoning by cyanides. The disturbance of what process became the most credible cause of the girl's death? Tissue respiration Synthesis of hemoglobin Transport of oxygen by hemoglobin Urea synthesis Transport of hydrogen with malate-aspartate shunt Питання №: 58The greater amount of nitrogen is excreted from the organism in form of urea. Inhibition of urea synthesis and accumulation of ammonia in blood and tissues are induced by the decreased activity of the following liver enzyme: Urease Aspartate aminotransferase Carbamoyl phosphate synthetase Pepsin Amylase Питання №: 59Transfer of a single electron to O2 generates the potentially damaging superoxide anion free radical, the destructive effects of which are amplified by its giving rise to free radical chain reactions. What enzyme is responsible for the removal of superoxide anion in all aerobic organisms (but not in obligate anaerobes) and protection of cells from its potential toxicity? Super oxidedismutase Glutathionereductase Peroxidase Catalase Glutathioneperoxidase Питання №: 60Choose from these carbohydrates the monosaccharide: Glycogen Maltose Starch Deoxyribose Sucrose One of the forms of innate human pathology is accompanied by the blockage of the conversion of phenylalanine into tyrosine. The biochemical manifestation of the disease is the accumulation of certain organic acids in the organism including: Phenylpyruvate Citrate Pyruvate Lactate Glutamate الحمد لله الذي بنعمته تتم الصالحات ����Еліва Еліва���� |