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    Питання №: 11


    A 4 y.o. boy has had recently serious viral hepatitis. Now there are such clinical presentations as vomiting, loss of consciousness, convulsions. Blood analysis revealed hyperammoniemia. Disturbunce of which biochemical process caused such pathological condition of the patient?

    Disturbed neutralization of ammonia in liver

    Disturbed neutralization of biogenic amines

    Increased putrefaction of proteins in bowels

    Activation of aminoacid decarboxylation

    Inhibition of transamination enzyms

    Питання №: 12


    A patient with encephalopathy was admitted to the neurological department. There was revealed a correlation between increasing of encephalopathy and substances absorbed by the bloodstream from the intestines. What substances that are formed in the intestines can cause endotoxemia?

    Ornithine

    Biotin

    Butyrate

    Acetacetate

    Indole

    Питання №: 13


    The signs of skin depigmentation of a 19-year-old patient are caused by the disorder of melanin synthesis. The disturbance of the metabolism of what amino acid is it caused by?

    Histamine

    Tryptophan

    Tyrosine

    Proline

    Lysine

    Питання №: 14


    After taking sulfonamides and aspirin by a 38-year-old patient, hemolysis of erythrocytes caused by the insufficiency of glucose-6-phosphate dehydrogenase developed. The disturbance of what coenzyme formation does this pathology result from?

    Ubiquinone

    FADH2

    Pyridoxal phosphate

    FMNH2

    NADPH2

    Питання №: 15


    Krebs cycle plays an essential role in the realization of gluconeogenic effect of certain amino acids. It is caused by the obligatory transformation of their anazotic carbon skeletons into:

    Malate

    Oxaloacetate

    Succinate

    Fumarate

    Citrate

    Питання №: 16


    Persons suffering from alcoholism get the bulk of calories with alcohol drinks. They usually have typical deficiency of thiamine (Wernicke-Korsakov syndrome) that impairs the function of the nervous system, leads to psychoses, loss of memory etc. The decreased activity of what enzyme is the cause of the development of this syndrome?

    Alcohol dehydrogenase

    Pyruvate dehydrogenase

    Transaminase

    Aldolase

    Hexokinase
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