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Which one of the following is the most common congenital heart defect to cause an initial left-to-right shunt? Tetralogy of Fallor Coarctation of the aorta @Ventricular septal defect Atrial septal defect Paten ductus arteriosus # 65 Bacterial myocarditis constitutes the greatest to patients who have which of the following forms of congenital heart disease? Atrial septal defect @Ventricular septal defect Pulmonic stenosis Tetralogy of Fallot Patent ductus arteriosus # 66 Which one of the following statements correctly describes the flow of blood in an individual with an atrial septal defect who develops Eisenmenger’s syndrome? Aorta to pulmonary artery to lungs to left atrium to left ventricle to aorta Left atrium to right atrium to right ventricle to lungs to left atrium Left ventricle to right ventricle to lungs to left atrium to right ventricle @Right atrium to left atrium to left ventricle to aorta to right atrium Right ventricle to left ventricle to aorta to right atrium to right ventricle # 67 A 2-year-old girl is being evaluated for growth and developmental delay. She has had several past episodes when she would suddenly have trouble breathing, become blue, and then assume a squatting position to catch her breath. Work-up finds a defect in the wall of the ventricular septum, increased thickness of the right ventricle, and dextroposition of the aorta. Which of the following cardiovascular abnormalities is most likely to be present in this child? Coarctation of the aorta Incompetence of the mitral valve Patency of the foramen ovale Persistence of the AV canal @Stenosis of the pulmonic valve # 68 A 2-month-old girl is being examined for a routine check-up. She was born at term, and there were no problems or complications during the pregnancy. The baby appeared normal at birth and has been asymptomatic. Physical examination at this time finds a soft systolic murmur with a systolic thrill. No cyanosis is present, and her peripheral pulses are thought to be within normal limits. An electrocardiogram reveals slight left ventricular hypertrophy. Which of the following is the most likely diagnosis? Coarctation of the aorta Patient ductus arteriosus Persistent truncus arteriosus Tetralogy of Fallot Ventricular septal defect # Konec: #end 69 A 60-year-old patient was diagnosed with hypothalamic lateral nuclei stroke. What changes in patient’s behavior may be expected? Thirst Aggressive behaviour Unsatisfied hunger @The rejection of food Depression # Rheumatic diseases # 1 What organism causes a rheumatic fever? @Streptococcus Staphylococcus Gonococcus Pneumococcus Clebsiella # 2 A 38 year old patient suffers from rheumatism in its active phas E. What laboratory characteristic of blood serum is of diagnostic importance in case of this pathology? @C-reactive protein Creatinine Urea Transferrin Uric acid # 3 What from the following clinico-morphological features does not typical for rheumatic fever? @The presence of focus of chronic infection Generalized vasculitis Disturbance of immune homeostasis Systemic progressive disorganization of connective tissue Acute flow # 4 Manifestations of rheumatic fever that are of major diagnostic value include all the following EXCEPT Sudcutaneous nodules Migratory arthritis of large joints @Fever Erythema marginatum Chorea minor # 5 A 7-year-old boy presents with the acute onset of fever, pain in several joints, and a skin rash. Physical examination finds an enlarged heart, several sudcutaneous nodules, and a skin rash on his back with a raised, erythematous margin. Laboratory tests find an elevated erythrocyte sedimentation rate and elevated anti-streptolysin O titers. Within the past month, this boy most likely had which one of the following infection? Pseudomonas aeruginosa infection of the aorta Streptococcus pneumonia infection of the lungs α-hemolytic streptococci infection of the oral cavity @β-hemolytic streptococci infection of the pharynx Staphylococcus aureus infection of the skin # 6 A 63-year-old man presents with signs of congestive heart failure, including shortness of death, cough, and paroxysmal nocturnal dyspnea. Physical examination reveals a hyperdynamic, bounding, “water-hammer” pulse and a decrescendo diastolic murmur. His hyperdynamic pulse causes “bobbing” of his head. Which of the following is the most frequent cause of the cardiac vascular abnormality present in this individual? Aortic dissection Infective endocarditis Latent syphilis Marfan syndrome @Rheumatic fever # 7 The most characteristic feature of chronic rheumatic heart disease is Endocarditis Myocarditis Pericarditis @Mitral valvulitis Pulmonic valvulitis # 8 Autopsy of a 58 y.o. man revealed that bicuspid valve was deformed, thickened and unclosed. Microscopically: foci of collagen fibrilla are eosinophilic, react positively to fibrin. The most probably it is: Amyloidosis Fibrinous inflammation Hyalinosis Mucoid swelling @Fibrinoid swelling # 9 A 30-year-old woman was hospitalized with symptoms of active rheumatic fever. She has died because of the increasing cardio-vascular insufficiency. The signs of decompensative chronic cardiac insufficiency were found during autopsy. Small foci of diffuse cardisclerosis were found in myocardium. The leafs of mitral valve were thickened and sclerotic with presence of thrombotic masses looked like warties. What type of endocarditis was @Diffuse Acute wart-like (verrucous) Fibroplastic Recurrent wartilike Polipous-ulcerative # 10 A histology investigation of a mitral valve sample of a patient who died from complications of rheumatism revealed a mucoid swelling, a damage of the endothelial cells and also thrombi at the valve closure line. Name the type of the rheumatic endocarditis? @Acute warty endocarditis Diffuse endocarditis Fibroplastic endocarditis Relapsing warty endocarditis Polyps-ulcerated endocarditis # 11 At the histological exam of the mitral valve were revealed: the mucoid edema, the damage of the endothelium and the formation of fibrin thrombi on the covering margin. What form of the rheumatic endocarditis is observed? @Acute verrucous endocarditis Diffuse endocarditis Fibroplastic endocarditis Recurrent-verrucous endocarditis Polypous-ulcerative endocarditis # 12 Histological investigation of the mitral valves of the heart revealed the focal desquamation of endothelial cells replaced by thrombi. The connective tissue had mucoid swelling areas and also zones of sclerosis and revascularization. Name the type of valve's endocarditis? @Relapsing warty endocarditis Diffuse endocarditis Acute warty endocarditis Fibroplastic endocarditis Polyps-ulcerated endocarditis # 13 A 56-year old male with a long history of a rheumatic heart insufficiency died with symptoms of hemiplegia shortly before death. Histological examination of his mitral; valve revealed severe sclerosis, nodular collection of inflammatory cells and vegetations composed mainly of platelets and fibrin. Name the most likely type of endocarditis? @Relapsing warty endocarditis Acute warty endocarditis Diffuse endocarditis Fibroplastic endocarditis Polyps-ulcerated endocarditis # 14 Physical examination of an asymptomatic 29-year-old woman with a history of rheumatic fever during childhood finds an early diastolic opening snap with a rumbling late diastolic murmur. Which of the following is the most likely diagnosis? Aortic regurgitation Aortic stenosis Mitral regurgitation @Mitral stenosis Pulmonic stenosis # 15 A 32-year-old female with a long history of rheumatic valve's defect presented at the hospital with tachypnea and dyspnea, leg's edema, ascites and hepatomegaly. She died from the chronic heart insufficiency. An autopsy revealed a mitral stenosis. What was the most likely factor of the mitral stenosis morphogenesis? @Leaves union between itself Sclerosis and bulge of leaves Sclerosis and shortening of leaves Shortening of tendon filaments Presence of small blood thromboses on the surface of valve # 16 In 46-year-old patient with rheumatic heart disease (mitral stenosis) the short-wind in low physical loading, tachycardia, cyanosis of lips, wet crepitation in the lower parts of lung and edema of legs have appeared. What histological changes are characteristic in the liver? @Necrosis of hepatocytes in the center of lobule; fatty degeneration in outlying districts Necrosis of hepatocytes in the center of lobule; hyaline degeneration in the outlying districts Fatty degeneration of hepatocytes in the center of lobule; necrosis in the outlying districts Hydropic degeneration of hepatocytes in the center of lobule, necrosis in the outlying districts Necrosis of hepatocytes in the center of lobule; hydropic degeneration in the outlying districts # 17 The most frequent cause of aortic valve incompetence and regurgitation is Latent syphilis Infective endocarditis @Rheumatic fever Aortic dissection Congenital # 18 During the section of a child, who died of heart failure, the dilatated ventricular cavities of the heart were revealed. Microscopically there were plethora, edema, and diffuse infiltrates of histiocytes, lymphocytes, neutrophiles and eosinophiles in the myocardial stroma. What is the most possible diagnosis? Focal intermediate exudative myocarditis @Diffuse intermediate exudative myocarditis Nodular productive myocarditis Intermediate productive myocarditis Alternative myocarditis # 19 Death of the patients in early stages of rheumatic fever because of acute cardiac insufficiency is connected with one of the following manifestations of the rheumatic fever: @Myocarditis Pericarditis Endocarditis Septic endocarditis Cardiosclerosis # 20 At the pathomorphologic exam of a man who died of heart insufficiency the following facts were revealed: mitral valves were deformed, thickened, with knitted margins; connective tissue is filled with diffuse nodules that consist of the areas of fibrinoid necrosis. Macrophagocytes that look like giant multinuclear cells aggregate around these areas. Lymphocytes and single plasmatic cells surround similar focuses. What granuloma was defined? Actinomycotic Tuberculous @Rheumatic Syphilitic Lepromatous # 21 At the section of a dead woman were detected the morphological manifestations of stenosis of the left atrioventricular aperture and the mitral valve insufficiency. Histologically: there were presented a focal cardiosclerosis and Ashof-Talalaev granulomas. What is the most possible diagnosis? Systemic lupus erythematous Scleroderma Dermatomyositis Nodular periarteritis @Rheumatism # 22 Microscopic investigation of the heart auricle from a patient with a history of mitral stenosis revealed the Achoff- Talalayev's bodies (granulomas). What was the most likely cause of the heart insufficiency supported by the histology results? @Rheumatic Atherosclerotic Syphilitic Innate Septic # 23 An autopsy of 48-year-old female revealed a mitral stenosis with valve's incompetence. Histological investigation showed the post- inflammatory cardiosclerosis and Aschoff-Talalayev nodes (granulomas). What is the most likely diagnosis? @Rheumatism Systemic scleroderma Dermatomyositis Nodular periarteritis Lupus erythematosus # 24 Ashoff-Talalaev’s granulomas, which are foci of fibrinoid necrosis that are surrounded by macrophages, are found out in perivascular tissue of myocardium in the result of autopsy of 30 year woman who had the diagnosis: rheumatic fever and who died of heart insufficiency. What type of granuloma is found? @Blooming granuloma Withered granuloma Cicatrized granuloma Epitheliod granuloma Giant cell granuloma # 25 Ashoff-Talalaev and fibroblasts granulomas, which are focuses of fibrinoid necrosis that are surrounded by macrophages, are found in perivascular tissue of myocardium in the result of autopsy of 30 year woman who had the diagnosis: rheumatic fever and who died of heart insufficiency. What type of granuloma is found? Blooming granuloma @Withered granuloma Cicatrized granuloma Epitheliod granuloma Giant cell granuloma # 26 An autopsy of a 34year-old patient with a long history of rheumatism, revealed the epicardial surface of the heart with shaggy exudate formed by grey strands which easily separate from underlying tissues and described as 'bread-and-butter' pericarditis ('hairy heart'). What is the most likely diagnosis? @Fibrinous pericarditis Purulent pericarditis Hemorrhagic pericarditis Proliferated pericarditis Catarrhal pericarditis # 27 A 9-year-old boy presented with painless, firm 1-2 mm nodules at the skin around ulnar and knee joints (at extensor's area). Biopsy investigation revealed a central area of fibrinoid necrosis of the connective tissue surrounded by lymphocytes and macrophages. What disease these nodules are characteristic for? @Rheumatism. Rheumatoid arthritis. Systemic scleroderma. Nodular periarteritis. Lupus erythematosus. # 28 In a patient with vasculitis, the finding of serum antineutrophil cytoplasmic autoantibodies that react by immunofluorescence staining in a perinuclear pattern is most suggestive of Giant cell arteritis @Classic polyarteritis nodosa Wegener’s granulomatosis Churg-Strauss syndrome Microscopic polyangiitis # 29 The necrotizing inflammation of the small gastrointestinal artery shown in the photomicrograph below is most likely due to Myasthenia gravis @Polyarteritis nodosa Atherosclerosis Dissection aneurysm Suphilis # 30 Microscopical investigation of arterioles showed plasmatic saturation, mucoid and fibrinoid swelling, fibrinoid necrosis of walls, diffuse infiltration by lymphocytes, plasmocytes and monocytes. In addition, the focal proliferation of hystiocytes, endotheliocytes and pericytes were determined. The final diagnosis was the "periarteritis nodosa". What type of inflammation took place in arterioles? @ Acute immune inflammation Acute not immune inflammation Focal exudative inflammation Diffusive exudative inflammation Fibrinous inflammation # 31 A 33-year old female died from chronic kidney failure. A post-mortem revealed multiple scars and infarcts in kidneys and spleen. Histological investigation showed alteration of small and medium sized arteries presented with sclerosis and mild endothelial proliferation. A severe lymphocytes and histiocytes infiltrates were also recognized at the perivascular tissues. What is the most likely disease caused these alterations? @Nodular periarteritis Atherosclerosis Hypertonic disease Morphine's Disease Visceral syphilis # 32 A 45-year-old woman has episodes of pain with swelling and warmth of her hands and feet that make it difficult for her to walk or to prepare meals. She develops painful subcutaneous nodules on the extensor surfaces other elbows. Over the years, her hands become deformed so that it is difficult to perform tasks as simple as opening a door or buttoning her blouse. Which of the following laboratory test findings is she most likely to have? HLA B27 ANA positive at 1:256 @Elevated rheumatoid factor Markedly decreased serum complement Hypogammaglobulinemia # 33 A 30-year-old woman is suffering from chronic inflammation of the hand joints. If the doctor suggests rheumatoid arthritis, what will be the most probable pathogenesis of the disease? @It is caused by immune complexes of IgM antibody against human IgG It is caused by release of histamine by mast cells, bound with IgE It is caused by CD4 T cells and macrophages invading the joints It is caused by the activity of superantigens that activate both humoral and cellular immune responses It is caused by the primary immune response to hepatitis B surface antigen # 34 A 30 y.o. woman had been ill for a year when she felt pain in the area of joints for the first time, they got swollen and skin above them became reddened. Provisional diagnosis is rheumatoid arthritis. One of the most probable causes of this disease is a structure alteration of a connective tissue protein: Troponin Ovoalbumin Mucin Myosin @Collagen # 35 A 63-year-old woman developed symptoms of rheumatoid arthritis. Their increase of which blood values indicators could be the most significant in proving the diagnosis? R-glycosidase Acid phosphatase Lipoproteids General cholesterol @Additive glycosaminoglycans # 36 After the undercooling of the patient, the deformation of the joints, painfulness, contraction of movements in the fingers of limbs has developed. Little solid nodules appeared around the joints. At the biopsy there were revealed the focuses of fibrinoid necrosis in the nodules that were surrounded by histiocytes. What is your diagnosis? @Rheumatoid arthritis Dermatomyositis Rheumatism Podagra Deforming arthrosis # 37 A 48-year-old female after exposure to cold presents to her physician with painful deformed fingers joints, which bones were restricted in their movements. Physical examination revealed small firm nodules near the joints. Histological investigation of the nodules biopsy showed the centrally located core of fibrinoid necrosis with surrounding rim of macrophages and hystiocytes. What is the most likely diagnosis? @Rheumatoid arthritis. Dermatomyositis. Rheumatism. Gout. Deformed arthrosis. # 38 A 62-year-old woman presents to her physician with considerable deformation of metacarpal phalangeal and feet joints. Histological examination of the soft tissues adjacent to the joints revealed a mucoid swelling of the connective tissue, areas of a fibrinoid necrosis surrounded by palisading epithelioid macrophages and sclerosis. Few 'rice bodies' were found within a synovial cavity. What is the most likely diagnosis? @Rheumatoid arthritis Rheumatism Behterev's Disease Hematogenic tuberculosis Gout # 39 A 43-year-old woman presents to her physician with pain and immobility of the bones in metacarpal phalangeal and feet joints. Similar complains in symmetric pattern were about ulnar and knee joints, though not so severe. Physical examination revealed pastous skin over the joints, a partial ankylosis of metacarpal phalangeal and feet joints, and also ulnar deviation of the hands and flexion- hypertension ('swan neck"or"walrus flipper") deformities of the fingers. In addition, movable firm, rubbery and tender 1cm hypodermic nodules were found in the phalangeal joints area. An aspirate of joint fluid showed increased turbidity and presence of white "grains" ("rice bodies"). Immunofluorescence also revealed the rhematoid factor. What is the most likely diagnosis? @Rheumatoid poliartritis Systemic disease of connective tissue Gout Osteoartrosis - # 40 A 44-year-old woman presents to her physician ulnar deviation of the hands and flexion- hypertension ('swan neck" or "walrus flipper") deformities of the fingers. Her metacarpal phalangeal joints are easily exposed to a dislocation and a subluxation. Microscopical examination revealed nodular proliferations of synovium, cartilage destruction and "pannus" formation. What is the most likely diagnosis? @Rheumatoid arthritis Rheumatic arthritis Osteoarthritis. Lupus erythematosus. - # 41 A 36-year-old woman present because of increasing pain in her hands and knees, which, she says, is worse in the morning. Physical examination finds her fingers to be swollen and stiff, and there is ulnar deviation of her metacarpophalangeal joints. A biopsy from her knee would likely show areas where hystiocytes were palisading around irregular areas of necrosis, as seen in the picture below. The biopsy would also likely show proliferation and hyperplasia of the synovium with destruction of the articular cartilage. Which one of the following terms best describes these pathologic changes? Eburnation Gumma @Pannus Spondylosis Tophus # 42 An autopsy of 61-year-old male with a history of rheumatoid arthritis revealed enlarged dense kidneys, which had yellowish-whitish color and waxy appearance. Grossly, foci of scars were recognized at kidneys surface. Microscopically, at the slides stained by Congo red, homogeneous pink masses at capillaries of glomeruli tufts, arterioles walls and arteries, basal membranes of tubuli and in stroma were found. Name the described complication of rheumatoid arthritis? @Secondary amyloidosis of kidneys. Postinfective glomerulonephritis. Quickly progressive glomerulonephritis. Acute necrotic nephrosis. Fibroplastic glomerulonephritis. # 43 True statsments about SLE include all of the following except one: Lupus is associated with autoantibodies to many nuclear components Supressor T cells dysfunction is believed to plat a role in pathogenesis An association with complement component dificiency (C2 and C4) has been shown @Organ damage in lupus is predominantly mediated by natural killer cells - # 44 A 38-year-old man has myalgias, erythematous skin rashes over his face, and arthralgias without evidence for joint deformities. He has a positive antinuclear antibody test with a speckled pattern. Additionally, he has high liters of autoantibodies to ribonucleoprotein (KNP antibodies). A serum creatine kinase is 661 U/L. He has no evidence of renal disease. Which of the following conditions is he most likely to have: Mixed connective tissue disease CREST syndrome Dennatomyositis Polymyositis @Systemic lupus erythematosus # 45 A post-mortem of a 19-year old female revealed multiple furuncles on her skin, a warty endocarditis of the heart valves (Libman-Sacks endocarditis), a focal hemorrhage under the endocardium, ulcerative stomatitis, esophagus ulcers, pneumonia, nephritis, and a spleen hyperplasia with a perivascular sclerosis. Morphological investigation of her brain showed areas of necrosis and signs of vasculitis within thalamus. What is the most likely diagnosis? @Lupus erythematosus Rheumatism. Septic endocarditis. Ischemic heart diseas Hypertensive disease. # 46 At the section of a 19-year-old woman, there were revealed the verrucous endocarditis of all valves, focal subendocardial hemorrhages, ulcerous stomatitis and esophagitis, pneumonia, nephritis, hyperplasia of the spleen with perivascular sclerosis, vasculitis, a necrosis in the area of the optic tuber and numerous furuncles. What is the most possible disease? Septic endocarditis Rheumatism @Systemic lupus erythematous Ischemic heart disease Hypertensive disease # 47 A post-mortem of a 25-year old woman who died from chronic kidney failure revealed a reddish malar rash ('butterfly rash') and small (up to 0,2 cm) pale tan spreading vegetations over the mitral valve surface. Histological investigation of kidneys showed foci of fibrinoid necrosis, eosinophilic deposits (hematoxylin bodies), "wire loop" lesions in the basement membrane of the glomerular tuft and karyorrhexis. What is the most likely diagnosis? @Lupus erythematosus. Nodular periarteritis. Rheumatism. Rheumatic arthritis. - # 48 Red-brownish stains are found on the symmetrical parts of both cheeks in the result of autopsy of 45 year dead woman. Heart is increased, leaflets of aortic valve are condensed and thickened, have thrombotic masses on its surface. Kidneys are increased. Medulla is duck red, cortex is gray-brownish with red half-transparent points. Histologically: “hemothoxilin bodies” are found in the nucleus of ductal epithelium; thickening of basal membranes of glomerular capillaries, which look like “wire-loops”, several places in capillaries have hyaline thrombus and focuses of fibrinoid necrosis. Which diagnosis is more possible? @Systemic lupus erythematosus Rheumatic heart disease Septic endocarditis Glomerulonephritis Atherosclerosis # 49 A post-mortem of 40-year old female who died from uremia revealed enlarged kidneys, which had a patchy pattern of their surface. Histological investigation of kidneys showed eosinophilic deposits (hematoxylin bodies), "wire loop" lesions in the basement membrane of the glomerular tuft, hyaline thrombi and foci of fibrinoid necrosis. Besides these, Libman-Sacks endorcarditis was also determined. What is the most likely pathology in kidneys? @Lupus erythematosus nephritis. Rheumatoid glomerulonephritis. Choleric glomerulonephritis. Sclerotic kidney. Terminal glomerulonephritis # 50 At the section of a 40-year-old woman, who died of uremia, there were detected enlarged, mottled kidneys with thickened capillary membranes of glomeruli that looked like wire stitches, focuses of fibrinoid necrosis of its walls and hyaline thrombi in the lumens. Nuclei had haematoxylin corpuscles. The heart was affected by Libman-Sacks endocarditis. What is the most possible renal affection? Sclerotic kidney Rheumatic glomerulonephritis Choleric glomerulonephritis @Lupoid nephritis Terminal glomerulonephritis # 51 At the section of a 25-year-old woman, who died of uremia, were detected enlarged, mottled kidneys with the focuses of haemorrhages. Pathohistologically there were revealed haematoxylin corpuscles, capillary membranes of glomeruli that looked like wire stitches, hyaline thrombi, focuses of fibrinoid necrosis and bulbous sclerosis in the renal vessels. What is the most possible diagnosis? Nodular periarteritis Systemic scleroderma Rheumatoid arthritis Rheumatic arthritis @Systemic lupus erythematous # 52 A 28-year old female died from uremia. A post-mortem revealed an enlarged kidneys, which had a patchy pattern with hemorrhages on there surface. Histological investigation showed eosinophilic deposits (hematoxilin bodies), "wire loop" lesions in the basement membrane of the glomerular tuft, hyaline thrombi and foci of fibrinoid necrosis and also 'onion skin' sclerosis at the spleen's vessels. What is the most likely diagnosis? @Lupus erythematosus. Rheumatism. Systemic scleroderma. Rheumatoid arthritis. Nodular periarteritis. # 53 At the patient with suspicion on a systemic disease a biopsy from a site of the skin tightening and restricted motility was taken. A histology investigation revealed all kinds of disorganization of connective tissue fibers with mild cellular reaction and also transition in excessive sclerosis and a hyalinosis. What is the most likely diagnosis? @Scleroderma Nodular periarteritis Lupus erythematosus Psoriasis Dermatomyositis # 54 The woman of 45 years within several years has difficulties at swallowing. She also notes the limitation of fingers movements at printing on the computer keyboard, though joints are not painful. Physical investigation revealed her "stony face" (no wrinkles) owing to tightening of the facial skin and restricted motion of the mouth. The skin biopsy showed a widespread fibrosis of a derma without inflammatory infiltration. Diagnose disease on the listed clinical and morphological data. @Scleroderma Lupus erythematosus Dermatomyositis Amyloidosis Rheumatic arthritis # 55 An 8-year-old boy presents with weakness and pain over several of his proximal muscle groups. Physical examination reveals periorbital edema along with a lilac discoloration around his eyes and erythema over his knuckles. A muscle biopsy reveals atrophic fibers located primarily at the periphery of muscle fiber fascicles. Laboratory tests find the presence of antibodies directed against the microvasculature of skeletal muscle. Which of the following is the most likely diagnosis? Ataxia-telangiectasia Becker muscular dystrophy Charcot-Marie-Tooth disease @Dermatomyositis McCardle’s disease # 56 A 35- year- old female presented her physician intermittent episodes of ischemia of her fingers, marked by pallor, paresthesias and pain, accompanied by tightening and thickening of the skin and poliarthralgia. Histological investigation of the skin biopsy from affected areas revealed mild epidermal atrophy, hyalinosis of collagen fibers within derma, scattered perivascular lymphocytes' infiltrates. Underlying skeletal muscles expressed interstitial edema, loss of cross-section striation, nidal necroses followed with petrification. What is the most likely diagnosis? @Dermatomyositis Systemic scleroderma Lupus erythematosus Nodular periarteritis Rheumatism # 57 A perivascular inflammatory infiltrate in skeletal muscle is likely to be seen in all the following EXCEPT Hypersensitivity angiitis Polymiositis Polyarteritis nodosa @Cystic medial necrosis Systemic sclerosis # 58 A post-mortem of the patient who died from uremia revealed deformation of a spine column with severe restriction of its mobility. Articular cartilages of spine joints were destructed with persistent chronic inflammation in tissues of joints. The joints cavities filled with connective tissue, in some places leading to ossification and ankylosis formation. In an aorta, heart, lungs a chronic inflammation and a focal sclerosis were discovered. In kidneys an amyloidosis was recognized. What diagnosis in this case is most probable? @Ankiloid spondiloartritis (the Behterev's disease) The Pedget's disease (deforming ostosis) Rheumatoid arthritis. Parathyroid osteodystrophy. Osteopetrosis (marble disease). # Konec: #end Acute diseases of Respiratory system # 1 |