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@Adenocarcinoma of uterus Placental polyps Acute endometritis Glandular hyperplasia of endometrium Chorioepithelioma of uterus # 94 A 48-year-old woman complains to her doctor of uterine bleeding. Endometrial biopsy investigation revealed a presence of gland-forming cells with enlarged hyperchromic nuclei, cell atypia, and abnormal mitoses. These cells were also determined at myometrium. What term most correctly identifies this pathological process? @ Adenocarcinoma of uterus. Adenomatous endometrial hyperplasia. Acute endometritis. Placental polyp. Chorionepitelioma of uterus. # 95 A 57-year-old patient gained periodical metrorrhagias. There was performed a diagnostical scrape of mucous membrane of uterus. Microscopically: among blood elements there are glandular complexes of different shape and size. These complexes consist of atypical cells with nuclear hyperchromia and numerous mitoses (including pathological ones). Name the diagnosis. @Adenocarcinoma Fibromyoma of uterus Chorionepithelioma Hyperplasia of endometrium glands Endometritis # 96 A 57 year old patient has periodic uterine bleedings. Diagnostic endometrectomy was performed. Biopsy material contains among the blood elements some glandular complexes of different sizes and forms that consist of atypic cells with hyperchromic nuclei and multiple mitoses (including pathological ones). What is the most probable diagnosis? Fibromyoma of uterus @Adenocarcinoma Chorioepithelioma Glandular hyperplasia of endometrium Endometritis # 97 A 55-year-old woman had a relapse uterine bleeding. A diagnostic smearing from the uterine mucosa was made. There, among blood elements, different form and size glandular elements were seen. They were formed of atypical cells with hyperchromic nuclei and have many mitoses (including pathological). What process can we think of? @Adenocarcinoma Glandular hyperplasia of endometrium Chorionepithelioma Adenomatous polyp Indications of breaked off pregnancy # 98 A female patient in a climacteric period presented with relapsing uterine bleedings. The diagnostic curettage of a uterus is executed. Microscopical investigation showed among blood glandular elements of different size and forms created by atypical cells with hyperchromatic nuclei numerous mitoses (including pathological). What is the most likely pathology? @Adenocarcinoma Glandular hyperplasia of endometrium Choriocarcinoma Adenomatous polypus Signs of the interrupted pregnancy # 99 A 70-year-old healthy man is found to have a palpable firm nodule in the prostate gland on digital rectal examination. His serum prostate specific antigen (PSA) is found to be 19 ng/mL. The microscopic appearance seen on biopsy of the prostate will probably be most consistent with which of the following conditions: Chronic prostatitis @Adenoearcinoma Infarction Leiomyoma Rhabdomyosarcoma # 100 A 45-year-old woman has an enlarged, non-tender lymph node that on biopsy reveals a metastatic neoplasm. Which of the following is the most likely primary neoplasm: Cerebral glioma @Adenocarcinoma of the colon Fibroadenoma of the breast Liposarcoma of the retroperitoneum Laryngeal papilloma # 101 A 59-year-old man went to his physician for a routine health maintenance examination. The only abnormal physical examination finding is a positive stool guaiac test. Laboratory studies show a CBC with Hgb 10.0 g/dL, Hct 29.S&, MCV 73 fL, platelet count 300,000/microliter, and WBC count 8700/microliter. He is found on colonoscopy to have a 4 cm mass lesion arising on the mucosal surface of the transverse colon. Which of the following statements is most appropriate regarding these findings? This is an uncommon site for a primary malignant neoplasm @Microscopically, the mass is probably an adenocarcinoma Persons who are smokers are at much greater risk to develop this lesion Hypercalcemia is a frequent paraneoplastic complication The predicted 5 year survival rate is less than 5% # 102 A 60-year-old woman has a firm mass with irregular borders felt in her left breast on a routine physical examination. A fine needle aspiration is performed and microscopic examination shows an infiltrating ductal carcinoma. A left mastectomy with axillary lymph node dissection is performed. A tissue sample of this neoplasm is submitted for microscopy. Which of the following does flow hystologicaly most likely provide? Squamous cell carcinoma with keratinisation Squamous cell carcinoma without keratinisation Mucous carcinoma @Adenocarcinoma Fibrous cancer # 103 A 64-year-old man has has noted a 10 kg weight loss along with increasing fatigue over the past year. He has experienced dull abdominal pain for the past week. He has developed abdominal distention with lack of stools in the past two days. On physical examination, bowel sounds are reduced. An abdominal CT scan reveals a mass involving the descending colon. At laparotomy, a partial resection of the left colon is performed, with removal of an encircling mass in the descending colon. Microscopically, the mass is found to be a high differentiated adenocarcinoma. Which of the following morphological type is most likely to be present in this man? @Tubular structures Trabecular structures Mucous Cancer’s perles Cellular atipism # 104 Histologic section from a 3 cm mass found in the mandible of a 55-year-old woman reveal a tumor consisting of nests of tumor cells that appear dark and crowded at the periphery of the nests and loose in the center (similar to the stellate reticulum of a developing tooth). Grossly, the lesions consist of multiple cyst filled with a thick, “motor oil” – like fluid. Which of the following is the most likely diagnosis? Pleomorphic adenoma Ameloblastoma Mucoepidermoid carcinoma @Adenoid cystic carcinoma Acinic cell carcinoma # 105 During the histological examination of the stomach tumour a great amount of signet-ring cells. Name the histological variant of the cancer was diagnosed. Sarcoma Solid carcinoma Adenocarcinoma @Mucous carcinoma Carcinoid # 106 A 52-year-old woman feels a lump in her right breast and goes to her physician. On physical examination there is a 3 cm right breast mass fixed to the chest. This mass is biopsied and on microscopic examination shows nests of cells with marked hyperchromatism and pleomorphism. Which are surrounded by connective stroma tissue in a great a mount. Name histological type of tumor: Adenocarcinoma @Skirrhous cancer Trabecular cancer Medullar cancer Undifferentiated cancer # 107 A 45-year-old woman has a small tumor of her left breast. Histological examination of a breast biopsy revealed poorly differentiated atypical epithelial cells. They formed trabecules separated from one another by connective tissue. The cells and stroma proportion was approximately 1:1 .What is the most likely histological variant of the cancer. @ Solid carcinoma. Adenocarcinoma. Epidermoid carcinoma. Sccirrhous fibrocarcinoma. Small cell carcinoma. # 108 A microscopical investigation of a breast tumour revealed that the neoplasm was constructed of undifferentiated atypical epithelial cells. These cells formed trabecules, separated by layers of a connective tissue. A parity of cells and stroma was approximately 1:1. Name a histological variant of a cancer. @ Solid carcinoma Adenocarcinoma Squamous cell carcinoma Fibrocarcinoma Small cell carcinoma # 109 At the histological examination of a mammary gland tumour was revealed. Thet it was built of low-differentiated atypical cells of epithelial genesis. They formed trabeculae that were parted from one another by connective tissue. The correlation between cells and stroma is approximately 1:1. Name the histological variant of the cancer. Squamous cells Adenocarcinoma @Solid Fibrous Small-cell # 110 A histological investigation of a breast tumor's biopsy revealed solid layers of fine epithelial cells with polymorphic nuclei and a considerable quantity of pathological mitoses. In addition, the tumor had very little stroma and a lymphocytic infiltration. Name the kind of presented tumor. @Medullary carcinoma Scirrhous carcinoma Paget's disease Adenoma Adenofibroma # 1101 "Fallout" from nuclear bomb testing and from nuclear power plant disasters may release radioactive isotopes into the environment. Exposure to radiation via ingestion ofstrontium-90 that can contaminate milk products may result in an increased risk for which of the following neoplasms: Kaposi's sarcoma @Small cell anaplastic carcinoma of lung Osteosarcoma Nasopharyngeal carcinoma Endometrial carcinoma # 112 A bronchoscopy of a 65-year-old patient revealed a polyp-like formation, 1,0 cm in diameter, in the proximal part of the upper lobe bronchus of his right lung. A histological research revealed the tumour which consisted from fine lymphocyte-like cells with hyperchromic nuclei. The cells grew like layers and cords. Specify, what of the listed below kinds of tumors is the most authentic? @Nondifferentiated small cell carcinoma Nondifferentiated large cell carcinoma Squamous cell carcinoma Adenocarcinoma Glandular squamous cell carcinoma # Mesenchymal tumours # 1 There was determined a solid, moveable tumour, neatly isolated from surrounding tissues. It was of white color when incised and was presented with fibrous tissue; microscopically there were seen chaotically set collagen fibres. There were little of cells. Term the tumour. Myoma @Fibroma Histiocytoma Dermatofibroma Desmoid # 2 A 30-year-old man has a node on his left leg the skin. Physical investigation revealed dense, mobile tumor, circumscribed by a connective tissue capsule. Grossly it cut section was presented with dense witish fibres. Microscopically the tumor composed of mature fibroblasts and a collagenous stroma. What is the most likely diagnosis? @Fibroma Myoma Histiocytoma Dermatofibroma Desmoid. # 3 Examination of a patient revealed a dense, movable skin tumour that is standing out distinctly from the surrounding tissues. Its section is found to be white and composed of fibrous tissu e. Microscopic examination revealed interlacing collagen fibers and few cells. What tumour is it? @Fibroma Myoma Histiocytoma Dermatofibroma Desmoid # 4 There was a tumour of skin found. The tumour is thick, movable, separated from adjacent tissues. On incision the tumour is white-coloured, and is made of reticular tissue. Microscopically: chaotically tangled colagen fibres, a few cells. Name the tumour. Dermatofibroma Myoma Histiocytoma @Fibroma Desmoid # 5 In the skin macroscopically was detected a solid moveable tumour. Microscopically it is presented by chaotically set fascicles of collagen fibres with a little amount of spindle cells. What tumour was removed? Glomus-angioma Leiomyoma Melanoma Lipoma @Solid fibroma # 6 At the young man in a skin depth the dense, mobile tumour, is defined. A microscopical research revealed chaotically located fascicles of collagen fibers with a small amount of spindle-shaped cells. What tumour is removed? @Dense fibroma. Leiomyoma. Melanoma. Lipoma. Glomus-angioma. # 7 A 33-year-old woman presented with a tumor-like formation on a white line of her abdomen, which during pregnancy has started to increase in sizes. A histological research revealed that a tumor is constructed of the differentiated connective tissue, in which collagen fibers prevail of cells. What tumor presented in this case? @ Desmoid Dense fibroma Fibrosarcoma Soft fibroma Dermatofibroma # 8 Examination of the anterior abdominal wall of a pregnant woman revealed a tumour-like formation that arose on the spot of a tumour that was removed two years ago. The neoplasm was well-defined, dense, 2х1 cm larg e. Histological examination revealed that the tumour was composed of differentiated connective tissue with prevailing collagen fibres. What tumour might be suspected? Hibernoma Lipoma @Desmoid Leiomyoma Fibrosarcoma # 9 A 23-year-old woman presents with a 0.4-cm firm brown lesion on her upper right thigh. Histologic sections from this lesion reveal an irregular area in the upper dermis that is composed of a mixture of fibroblasts, hystiocytes, stromal cells, and capillaries. The majority of cells of cells in this mixture are fibroblasts. The overlying epidermis reveals hyperplasia of the basal layers. Which of the following is the most likely diagnosis? @Dermatofibroma Dermatofibrosarcoma protuberans Fibroxanthoma Pyogenic granuloma Sclerosing hemangioma # 10 A painless new growth without neat borders appeared in soft tissues of left thigh in a young man. At the biopsy material the tissues of the formation look like fish meat, consist of embryonic fibroblast-like cells with many mitoses that grow through the muscles. What is your diagnosis? @Fibrosarcoma Myosarcoma Fibroma Cancer Myoma # 11 The patient, a previously dealthy man of 25 years, presented with a painless neoplasm in a soft tissues of his left thigh. Grossly, a tumor had uneven boundaries and on cut section it looked like a fish flesh. Microscopic investigation revealed immature connective tissue cells with pleomorphism, numerous mitotic figures and lymphocyte infiltration at the edge of the tumor. What is the most likely diagnosis? @Fibrosarcoma Myosarcoma Fibroma Carcinoma Myoma # 12 A young man incurs a stab wound to the chest. The wound is treated in the emergency room. Two months later there is a firm, 3x2 cm nodular mass with intact overlying epithelium in the region of the wound. The scar is firm, but not tender, with no erythema. The mass is excised and microscopically is found to he composed of fibroblasts with abundant collagen. By which of the following mechanisms has this series of events most likely occurred: Hypertrophic scar (keloid) formation @Development of a fibrosarcoma Poor wound healing from diabetes mellitus Foreign body response from suturing Staphylocccal wound infection # 13 A 55-year-old woman has a moveable formation (1x0,7 cm) of a pasty consistence with neat borders and slow growth under the skin of submandibular area. Histologically were detected the lipocytes, which formed lobules that differ in form and size. Thin strata of connective tissue with vessels determined the lobules. Make a diagnosis. Angioma Fibroma @Lipoma Liposarcoma Fibrosarcoma # 14 A 48-year-old man presented to physician with mobile 1, 0 x 0, 7 cm formation under a skin of mandible. It had precise borders, dough-like consistence and slow growth. A histologic research of formation revealed fat tissue cells (lipocytes), which created lobules of different forms and the sizes, divided by thin layers of a connective tissue with vessels. What is the most likely diagnosis? @ Lipoma Fibroma Angioma Liposarcoma Fibrosarcoma # 15 Examination of a 55 year old woman revealed under the skin of submandibular area a movable slowly growing pasty formation with distinct borders 1,0x0,7 cm large. Histological examination revealed lipocytes that form segments of diffrent forms and sizes separated from each other by thin layers of connective tissue with vessels. What is the most probable diagnosis? Angioma Liposarcoma Fibrosarcoma @Lipoma Fibroma # 16 A 40-year-old woman presented with a very slowly enlarging subcutaneous mass at the right side of the chest wall. Physical examination revealed a soft lobulated fluctuant swelling, not attached to the skin or underlying muscle. Histologically a neoplasm was well-encapsulated and consisted of mature cells with clear cytoplasm that varied considerably in size. What is the most likely diagnosis? |