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  • Define a kind of inflammation

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    What is the most likely form of granuloma?

    @ Giant - cell granuloma

    Macrophagal

    Foreign body granuloma

    Epithelioid cells

    -

    #

    21

    A 56-year-old man has had increasing dyspnea for 6 years. He has no cough or fever. He was inhaling silica dust for many years in his job. A chest x-ray now shows increased intersitital markings and parenchymal 1 to 3 cm nodules. His pulmonary problems are most likely to be caused by which of the following inflammatory processes?

    Neutrophilic infiltration with release of leukotrienes

    @Foreign body giant cell formation

    Plasma cell production of immunoglobulin

    Histamine release by mast cells

    Release of growth factors by macrophages

    #

    22

    A 40-year-old woman had bilateral silicone breast implants placed two years ago. Since that time, she has noted increased firmness with slight deformity of the breast on the left. The implants are removed, and there is evidence for leakage of the implant contents on the left. Which of the following cell types is most likely to be most characteristic of the inflammatory response in this situation?

    Mast cell

    Eosinophil

    @Giant cell

    Neutrophil

    Plasma cell

    #

    23

    A histological investigation of enlarged neck lymphatic node revealed a congestion of epithelial cells, lymphocytes and giant Pirogov-Langhan's cells. In the center of lesion a caseous necrosis was present. Which pattern of inflammation do the lymphatic nodes display?

    @ Tuberculosis

    Rhinoscleroma

    Sarcoidosis

    Glanders.

    Syphilis.

    #

    24

    A 30-year-old male has a neck lymph node removed for examination. Histological investigation revealed granulomas, which consisted of epithelioid, lymphoid and multinuclear Langhans giant cells. Granulomas' centers were presented with necrosis. What causative agent needs to be revealed in the necrosis zone for support of the diagnosis of tuberculosis?

    @Mycobacterium tuberculosis

    Treponema pallidum

    Staphylococcus

    Frisch bacillus

    Salmonella

    #

    25

    A 28-year-old male presented to the hospital with a fever and weakness, (asthenia). A biopsy was taken from one of his enlarged neck lymph nodes for histological examination. Microscopic investigation revealed the foci of necrosis, surrounded by epithelioid cells, giant multinuclear Langhans' cells and also lymphocytes. What is the most likely diagnosis?

    @Tuberculosis

    Hodgkin's disease

    Lympholeukemia

    Sarcoidosis

    Syphilis

    #

    26

    A 7-year-old child, with a history of angina, presented with enlarged paratracheal, bifurcation and neck lymph nodes. A histological examination of his neck lymph node revealed the foci of necrosis, surrounded by lymphocytes, epithelioid cells and Pirogov-Langhans' cells. Which one is the most likely pathology?

    @Tuberculosis

    Sarcoidosis

    Rhinoscleroma

    Malleus

    Syphilis

    #

    27

    The histological examination of a lung tissue revealed a lesion presented with a locus of necrosis, surrounded by regular lines of epithelioid, lymphoid cells, plasma cells, macrophages and giant Pirogov-Langhans' cells.


    Define a kind of inflammation?

    @Tuberculosis inflammation

    Banal productive inflammation

    Inflammation at a lepra

    Exudative inflammation

    Alterative inflammation

    #

    28

    A 47-year-old male presented with a sub-febrile temperature and enlarged lymph nodes. A biopsy investigation of a lymph node revealed numerous granulomas with a caseous necrosis in the centers, surrounded by epithelioid cells, giant multinuclear Langhans' cells and lymphocytes.


    What is the most likely diagnosis?

    @Tuberculosis

    Lymphogranulomatosis

    Lymphosarcoma

    Lympholeukemia

    Simple lymphadenitis

    #

    29

    Histological investigation of a skin biopsy revealed granulomas, which consisted of epithelioid cells, surrounded mainly by T-lymphocytes. In addition, few giant multinucleated cells (Langhans' cells) were determined among epithelioid cells. The caseous necrosis was diagnosed within the centers of granulomas. There was lack of blood vessels. What is the most likely disease?

    @Tuberculosis

    Syphilis

    Lepra

    Rinoskleroma

    Glanders (malleus)

    #

    30

    Microscopic investigation an elderly man's lungs revealed the foci of necrosis, surrounded by the bank of epithelioid cells and lymphocytes. Between lymphocytes and epithelioid cells the rounded giant cells, with a considerable quantity of nuclei, located on a periphery of a lesion were determined. Give the name for these changes:

    @Tuberculous granuloma

    Sarcoid granuloma

    Syphilitic granuloma

    Lepromatous granuloma

    Scleromatous granuloma

    #

    31

    A 18-year-old girl had a neck lymphatic node removal at the biopsy procedure. Histological investigation showed nodules, consisted of banks of epithelioid, lymphoid cells and large multinucleated cells (Langhans' cells), located between them. In the centers of nodes a caseous necrosis was determined. What causative agent needs to be revealed in the necrosis zone for making final diagnosis?

    @Koch's mycobacterium

    Mycobacterium leprae

    Treponema pallidum

    Rickettsia

    Fungi

    #

    32

    An autopsy of 32-year-old male revealed slightly swollen and hyperemic lungs, covered with numerous millet-like grayish nodules. Histological investigation determined lesions consisted of lymphoid, epithelioid and Langhans giant cells. What is the most likely diagnosis?

    @Tuberculosis

    Croupous pneumonia

    Bronchopneumonia

    Interstitial pneumonia

    Bronchiectatic disease

    #

    33

    A sample of cervix uteri was taken for histological examination. A microscopical investigation revealed a tissue's inflammatory infiltration with vascular walls involvement of small vessels, arteries and veins. In addition, there were also determined a presence of plasma cells, lymphocytes, epithelioid cells in the infiltrate and foci of sclerosis and hyalinosis of tissue. What is the most likely disease?

    @Syphilis

    Tuberculosis

    Leukoplakia

    Erosio colli uteri

    Condyloma

    #

    34

    A histological investigation of a liver biopsy revealed granulomas, consisted of plasma cells and lymphoid cells. Small vessels were characterized by endo - and perivasculitis. Some foci of caseous necrosis were also determined. Such granulomas are typical for:

    @Syphilis

    Tuberculosis

    Lepra

    Rinoskleroma

    Glanders (malleus)

    #

    35

    A young man was operated because of phimosis. Histological investigation of a removed prepuce revealed polymorphic infiltrates, consisted of randomly located plasmocytes, epithelioid and lymphoid cells. The vasculitis was diagnosed in vessels. What disease such changes are characteristic for?

    @Syphilis

    Tuberculosis

    Actinomycosis

    Periarteritis nodosa

    Lepra

    #

    36

    Biopsy of an oral cavity's ulcer presented for a histological research. A microscopical investigation revealed areas of caseous necrosis, surrounded by plasmocytes, epithelioid, lymphoid cells and few giant multinuclear Pirogov-Langhans cells. There were also small vessels with signs of endo- and perivasculitis. Choose the most likely diagnosis.

    @ Syphilis

    Tuberculosis

    Lepra

    Rinoskleroma

    Glanders (malleus)

    #

    37

    An inflammatory process that has continued for 3 months includes the transformation of tissue macrophages to epithelioid cells. There are also lymphocytes present. Over time, fibroblasts lay down collagen as the focus of inflammation heals. These events are most likely to occur as an inflammatory response to which of the following infectious agents?

    @Mycobacterium leprae

    Pseudomonas aeruginosa

    Cytomegalovirus

    Giardia lamblia

    Treponema pallidum

    #

    38

    Histological examination of a skin tissue sampling revealed granulomas consisting of macrophagal nodules with lymphocytes and plasmatic cells. There are also some big macrophages with fatty vacuoles containing causative agents of a disease packed up in form of spheres (Virchow's cells). Granulation tissue is well vascularize D. What disease is this granuloma typical for?

    Glanders

    Syphilis

    Rhinoscleroma

    Tuberculosis

    @Lepra

    #

    39

    A 46-year-old woman living in western Texas presents with the slow development of numerous macules and nodules on her face. Physical examination finds a peripheral neuropathy with enlarged palpable nerves. A biopsy from a one of the skin nodules reveals aggregates of foam cells within the dermis. Special stains reveal rare acid-fast bacilli within peripheral nerves. Which of the following is the most likely diagnosis?

    @Leprosy

    Nocardiosis

    Sarcoidosis

    Syphilis

    Tuberculosis

    #

    40

    A skin sample was taken for histological research. Microscopical investigation revealed granulomas, consisted of macrophages' knots with adding of lymphocytes and plasma cells. There were also determined large macrophages with fatty vacuoles, which contained packed layers of causative agents of a disease (Virchow's cells). For what disease the given description is characteristic?

    @Lepra

    Tuberculosis

    Syphilis

    Rinoskleroma

    Glanders (malleus)

    #

    41

    As a result of a microscopic examination of the fragment of the skin the granulomas were found out; they composed of a lot of macrophages with a few amount of lymphocytes and plasma cells. Besides large macrophages with fat vacuoles occurred, the microorganisms were packed in those vacuoles as “cigars in the box” (Virchow’s cells). Granulation tissue had a good vascularization. What disease are such granulomas

    @Leprosy

    Tuberculosis

    Syphilis

    Rhinoscleroma.

    Actinomycosis.

    #

    42

    An elderly man presented to his physician with the complicated nasal breathing. The histological investigation of a biopsy from his nose septum revealed granulomatous inflammation in the mucosa with groups of large vacuolated histiocytes containing bacteria (Mikulicz's cells). What is the most likely diagnosis?

    @Rhinoscleroma

    Syphilis

    Tuberculosis

    Malleus

    Lepra

    #

    43

    A histological examination of biopsy from the nose mucous revealed epithelioid cells, plasmocytes, Mikulicz cells, and eosinophilic (acidophilic, Russell's) bodies. What is the most likely diagnosis?

    @ Rhinoscleroma

    Syphilis

    Tuberculosis

    Droplet infection

    Allergic rhinitis

    #

    44

    Histological investigation of a biopsy revealed a granuloma, consisted of lymphocytes, plasma cells, macrophages with foamy cytoplasm (Mikulicz's cells) and numerous hyaline's sphere- like aggregates. About what disease it is possible to think?

    @Rinoskleroma

    Lepra

    Syphilis

    Tuberculosis

    Actinomycosis

    #

    45

    A 43-year-old patient complains of hindered nasal breathing. Histological investigation of a biopsy of his nasal cavity mucosa revealed lymphoid cells, epithelioid cells, plasma cells and Mikulicz's cells. What is the most likely diagnosis?

    @Rinoskleroma

    Glanders (malleus)

    Tuberculosis

    Lepra

    Syphilis

    #

    46

    During the histological examination of the biopsy it was found out the granulomas composing of lymphocytes, epithelioid cells, plasma cells, macrophages with foamy pale cytoplasm (Mikulicz’s cells), and a lot of hyaline balls. What disease do you think about?

    @Rhinoscleroma.

    Leprosy.

    Syphilis.

    Tuberculosis.

    Actinomycosis.

    #

    47

    At the biopsy material of the nasal mucous membrane epithelioid cells, plasmocytes, Mikulicz’s cells, eosinophilic Russell’s corpuscles were detected. What is your diagnosis?

    Allergic rhinitis

    Syphilis

    Tuberculosis

    Respiratory-syncytial infection

    @Rhinoscleroma

    #

    48

    A 46-year-old patient complained of hard nasal breathing. The mucous membrane of the nose is thickened. At the biopsy material were revealed Mikulicz’s cells, the aggregation of epithelioid cells, plasmocytes, lymphocytes, hyaline spheres. What is your diagnosis?

    Adenoviral rhinitis

    @Scleroma

    Allergic rhinitis

    Rhino viral infection

    Meningocococcal nasopharyngitis

    #

    49

    A 46-year-old man complains of difficulties with nasal breathing. Mikulicz's cells, accumulation of epithelioid cells, plasmocytes, lymphocytes, hyaline balls were discovered in the biopsy material of the thickened nasal mucosa. What is the most likely diagnosis?

    Rhinovirus infection

    Meningococcal nasopharyngitis

    Allergic rhinitis

    @Scleroma

    Virus rhinitis

    #

    50

    A 54-year-old patient complains of complicated nasal breathing. A nasal mucosa was thickened. Histological investigation of a biopsy revealed Mikulicz's cells, epithelioid cells, plasma cells, lymphoid cells, and hyaline sphere- like aggregates. What is the most likely diagnosis?

    @Skleroma

    Adenoviral rhinitis

    Allergic rhinitis

    Rhinoviral infection

    Meningococcal nasopharyngitis

    #

    51

    A 22-year-old patient was admitted to the hospital with complaints of heavy nasal breathing. During the examination of her nasal cavity the doctors found thickened mucous membrane, a lot of mucus and nodular infiltrates without erosions in the nose.The nasal rhinoscleroma was diagnosed. The biopsy was taken. What typical morphological changes may be found?

    Granulomas with Langhan’s cells

    @Granulomas with Mikulicz’s cells

    Granulomas with Virchow’s cells

    Granulomas with foreign body cells

    Interstitial inflammation

    #

    52

    A patient, who had complains of dyspnoae, was done a biopsy of the nasal mucous membrane. The diagnosis was made – rhinoscleroma. What cells are typical for this illness?

    Plasmocytes

    Pirogov-Langhans’ cells

    @Mikulicz’s cells

    Lymphocytes

    Schaumann’s corpuscles

    #

    53

    At a 45-year-old man the biopsy procedure of his nasal cavity's mucosa was performed. The diagnosis of rhinoscleroma made. What cells are typical for the disease?

    @Mikulicz's cells

    Pirogovs' - Langhans' cells

    Plasma cells

    Lymphocytes

    Schaumann"s bodies

    #

    54

    A 40-year-old man presented with hyperemia and edema of skin in the neck region. In course of time a small abscess developed there. The focal was solid of yellow-green color. White grains could be seen in the purulent mass. Histological examination showed there druses of fungi, plasmatic and xanthoma cells, macrophages. Indicate the most possible kind of mycosis.

    Sporotrichosis

    Aspergillar

    Candidiasis

    @Actinomycosis

    Coccidioidomycosis

    #

    55

    A 40 year old man gained plethora and swelling on his neck. Some time after it developed into a small abscess. On incision nidus is thick, yellowish-green coloured. In purulent masses small white grains can be seen. Histologically: fungi mycelia, plasma cells, xantome cells, macrophages are revealed. What is the most probable type of mycosis?

    @Actinomycosis

    Aspergillosis

    Candidosis

    Sporotrichosis

    Coccidiomycosis

    #

    56

    Microscopical examination of an infiltrate removed from the submandibular skin area of a 30 y.o. man revealed foci of purulent fluxing surrounded by maturing granulations and mature connective tissue, the pus contains druses consisting of multiple short rod-like elements with one end attached to the homogenous centr E. What disease is it?

    @Actinomycosis

    Tuberculosis

    Syphilis

    Candidosis

    -

    #

    57

    Recovery of an organism from an infectious disease is accompanied by neutralization of antigens by specific antibodies. What cells produce them?

    Tissue basophils

    Fibroblasts

    @Plasmocytes

    T-lymphocytes

    Eosinophils

    #

    58

    The woman of 37 years old during one year periodically had infectious diseases of a bacterial genesis, their current was during the long term, the remissions - short-term. The hypogamaglobulinemia is found out during the inspection. Which infringement of function of the cells can be its direct reason?

    @Plasma cells

    Phagocytes

    Neutrophils

    Macrophages

    Lymphocytes

    #

    59

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