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What is the most likely form of granuloma? @ Giant - cell granuloma Macrophagal Foreign body granuloma Epithelioid cells - # 21 A 56-year-old man has had increasing dyspnea for 6 years. He has no cough or fever. He was inhaling silica dust for many years in his job. A chest x-ray now shows increased intersitital markings and parenchymal 1 to 3 cm nodules. His pulmonary problems are most likely to be caused by which of the following inflammatory processes? Neutrophilic infiltration with release of leukotrienes @Foreign body giant cell formation Plasma cell production of immunoglobulin Histamine release by mast cells Release of growth factors by macrophages # 22 A 40-year-old woman had bilateral silicone breast implants placed two years ago. Since that time, she has noted increased firmness with slight deformity of the breast on the left. The implants are removed, and there is evidence for leakage of the implant contents on the left. Which of the following cell types is most likely to be most characteristic of the inflammatory response in this situation? Mast cell Eosinophil @Giant cell Neutrophil Plasma cell # 23 A histological investigation of enlarged neck lymphatic node revealed a congestion of epithelial cells, lymphocytes and giant Pirogov-Langhan's cells. In the center of lesion a caseous necrosis was present. Which pattern of inflammation do the lymphatic nodes display? @ Tuberculosis Rhinoscleroma Sarcoidosis Glanders. Syphilis. # 24 A 30-year-old male has a neck lymph node removed for examination. Histological investigation revealed granulomas, which consisted of epithelioid, lymphoid and multinuclear Langhans giant cells. Granulomas' centers were presented with necrosis. What causative agent needs to be revealed in the necrosis zone for support of the diagnosis of tuberculosis? @Mycobacterium tuberculosis Treponema pallidum Staphylococcus Frisch bacillus Salmonella # 25 A 28-year-old male presented to the hospital with a fever and weakness, (asthenia). A biopsy was taken from one of his enlarged neck lymph nodes for histological examination. Microscopic investigation revealed the foci of necrosis, surrounded by epithelioid cells, giant multinuclear Langhans' cells and also lymphocytes. What is the most likely diagnosis? @Tuberculosis Hodgkin's disease Lympholeukemia Sarcoidosis Syphilis # 26 A 7-year-old child, with a history of angina, presented with enlarged paratracheal, bifurcation and neck lymph nodes. A histological examination of his neck lymph node revealed the foci of necrosis, surrounded by lymphocytes, epithelioid cells and Pirogov-Langhans' cells. Which one is the most likely pathology? @Tuberculosis Sarcoidosis Rhinoscleroma Malleus Syphilis # 27 The histological examination of a lung tissue revealed a lesion presented with a locus of necrosis, surrounded by regular lines of epithelioid, lymphoid cells, plasma cells, macrophages and giant Pirogov-Langhans' cells. Define a kind of inflammation? @Tuberculosis inflammation Banal productive inflammation Inflammation at a lepra Exudative inflammation Alterative inflammation # 28 A 47-year-old male presented with a sub-febrile temperature and enlarged lymph nodes. A biopsy investigation of a lymph node revealed numerous granulomas with a caseous necrosis in the centers, surrounded by epithelioid cells, giant multinuclear Langhans' cells and lymphocytes. What is the most likely diagnosis? @Tuberculosis Lymphogranulomatosis Lymphosarcoma Lympholeukemia Simple lymphadenitis # 29 Histological investigation of a skin biopsy revealed granulomas, which consisted of epithelioid cells, surrounded mainly by T-lymphocytes. In addition, few giant multinucleated cells (Langhans' cells) were determined among epithelioid cells. The caseous necrosis was diagnosed within the centers of granulomas. There was lack of blood vessels. What is the most likely disease? @Tuberculosis Syphilis Lepra Rinoskleroma Glanders (malleus) # 30 Microscopic investigation an elderly man's lungs revealed the foci of necrosis, surrounded by the bank of epithelioid cells and lymphocytes. Between lymphocytes and epithelioid cells the rounded giant cells, with a considerable quantity of nuclei, located on a periphery of a lesion were determined. Give the name for these changes: @Tuberculous granuloma Sarcoid granuloma Syphilitic granuloma Lepromatous granuloma Scleromatous granuloma # 31 A 18-year-old girl had a neck lymphatic node removal at the biopsy procedure. Histological investigation showed nodules, consisted of banks of epithelioid, lymphoid cells and large multinucleated cells (Langhans' cells), located between them. In the centers of nodes a caseous necrosis was determined. What causative agent needs to be revealed in the necrosis zone for making final diagnosis? @Koch's mycobacterium Mycobacterium leprae Treponema pallidum Rickettsia Fungi # 32 An autopsy of 32-year-old male revealed slightly swollen and hyperemic lungs, covered with numerous millet-like grayish nodules. Histological investigation determined lesions consisted of lymphoid, epithelioid and Langhans giant cells. What is the most likely diagnosis? @Tuberculosis Croupous pneumonia Bronchopneumonia Interstitial pneumonia Bronchiectatic disease # 33 A sample of cervix uteri was taken for histological examination. A microscopical investigation revealed a tissue's inflammatory infiltration with vascular walls involvement of small vessels, arteries and veins. In addition, there were also determined a presence of plasma cells, lymphocytes, epithelioid cells in the infiltrate and foci of sclerosis and hyalinosis of tissue. What is the most likely disease? @Syphilis Tuberculosis Leukoplakia Erosio colli uteri Condyloma # 34 A histological investigation of a liver biopsy revealed granulomas, consisted of plasma cells and lymphoid cells. Small vessels were characterized by endo - and perivasculitis. Some foci of caseous necrosis were also determined. Such granulomas are typical for: @Syphilis Tuberculosis Lepra Rinoskleroma Glanders (malleus) # 35 A young man was operated because of phimosis. Histological investigation of a removed prepuce revealed polymorphic infiltrates, consisted of randomly located plasmocytes, epithelioid and lymphoid cells. The vasculitis was diagnosed in vessels. What disease such changes are characteristic for? @Syphilis Tuberculosis Actinomycosis Periarteritis nodosa Lepra # 36 Biopsy of an oral cavity's ulcer presented for a histological research. A microscopical investigation revealed areas of caseous necrosis, surrounded by plasmocytes, epithelioid, lymphoid cells and few giant multinuclear Pirogov-Langhans cells. There were also small vessels with signs of endo- and perivasculitis. Choose the most likely diagnosis. @ Syphilis Tuberculosis Lepra Rinoskleroma Glanders (malleus) # 37 An inflammatory process that has continued for 3 months includes the transformation of tissue macrophages to epithelioid cells. There are also lymphocytes present. Over time, fibroblasts lay down collagen as the focus of inflammation heals. These events are most likely to occur as an inflammatory response to which of the following infectious agents? @Mycobacterium leprae Pseudomonas aeruginosa Cytomegalovirus Giardia lamblia Treponema pallidum # 38 Histological examination of a skin tissue sampling revealed granulomas consisting of macrophagal nodules with lymphocytes and plasmatic cells. There are also some big macrophages with fatty vacuoles containing causative agents of a disease packed up in form of spheres (Virchow's cells). Granulation tissue is well vascularize D. What disease is this granuloma typical for? Glanders Syphilis Rhinoscleroma Tuberculosis @Lepra # 39 A 46-year-old woman living in western Texas presents with the slow development of numerous macules and nodules on her face. Physical examination finds a peripheral neuropathy with enlarged palpable nerves. A biopsy from a one of the skin nodules reveals aggregates of foam cells within the dermis. Special stains reveal rare acid-fast bacilli within peripheral nerves. Which of the following is the most likely diagnosis? @Leprosy Nocardiosis Sarcoidosis Syphilis Tuberculosis # 40 A skin sample was taken for histological research. Microscopical investigation revealed granulomas, consisted of macrophages' knots with adding of lymphocytes and plasma cells. There were also determined large macrophages with fatty vacuoles, which contained packed layers of causative agents of a disease (Virchow's cells). For what disease the given description is characteristic? @Lepra Tuberculosis Syphilis Rinoskleroma Glanders (malleus) # 41 As a result of a microscopic examination of the fragment of the skin the granulomas were found out; they composed of a lot of macrophages with a few amount of lymphocytes and plasma cells. Besides large macrophages with fat vacuoles occurred, the microorganisms were packed in those vacuoles as “cigars in the box” (Virchow’s cells). Granulation tissue had a good vascularization. What disease are such granulomas @Leprosy Tuberculosis Syphilis Rhinoscleroma. Actinomycosis. # 42 An elderly man presented to his physician with the complicated nasal breathing. The histological investigation of a biopsy from his nose septum revealed granulomatous inflammation in the mucosa with groups of large vacuolated histiocytes containing bacteria (Mikulicz's cells). What is the most likely diagnosis? @Rhinoscleroma Syphilis Tuberculosis Malleus Lepra # 43 A histological examination of biopsy from the nose mucous revealed epithelioid cells, plasmocytes, Mikulicz cells, and eosinophilic (acidophilic, Russell's) bodies. What is the most likely diagnosis? @ Rhinoscleroma Syphilis Tuberculosis Droplet infection Allergic rhinitis # 44 Histological investigation of a biopsy revealed a granuloma, consisted of lymphocytes, plasma cells, macrophages with foamy cytoplasm (Mikulicz's cells) and numerous hyaline's sphere- like aggregates. About what disease it is possible to think? @Rinoskleroma Lepra Syphilis Tuberculosis Actinomycosis # 45 A 43-year-old patient complains of hindered nasal breathing. Histological investigation of a biopsy of his nasal cavity mucosa revealed lymphoid cells, epithelioid cells, plasma cells and Mikulicz's cells. What is the most likely diagnosis? @Rinoskleroma Glanders (malleus) Tuberculosis Lepra Syphilis # 46 During the histological examination of the biopsy it was found out the granulomas composing of lymphocytes, epithelioid cells, plasma cells, macrophages with foamy pale cytoplasm (Mikulicz’s cells), and a lot of hyaline balls. What disease do you think about? @Rhinoscleroma. Leprosy. Syphilis. Tuberculosis. Actinomycosis. # 47 At the biopsy material of the nasal mucous membrane epithelioid cells, plasmocytes, Mikulicz’s cells, eosinophilic Russell’s corpuscles were detected. What is your diagnosis? Allergic rhinitis Syphilis Tuberculosis Respiratory-syncytial infection @Rhinoscleroma # 48 A 46-year-old patient complained of hard nasal breathing. The mucous membrane of the nose is thickened. At the biopsy material were revealed Mikulicz’s cells, the aggregation of epithelioid cells, plasmocytes, lymphocytes, hyaline spheres. What is your diagnosis? Adenoviral rhinitis @Scleroma Allergic rhinitis Rhino viral infection Meningocococcal nasopharyngitis # 49 A 46-year-old man complains of difficulties with nasal breathing. Mikulicz's cells, accumulation of epithelioid cells, plasmocytes, lymphocytes, hyaline balls were discovered in the biopsy material of the thickened nasal mucosa. What is the most likely diagnosis? Rhinovirus infection Meningococcal nasopharyngitis Allergic rhinitis @Scleroma Virus rhinitis # 50 A 54-year-old patient complains of complicated nasal breathing. A nasal mucosa was thickened. Histological investigation of a biopsy revealed Mikulicz's cells, epithelioid cells, plasma cells, lymphoid cells, and hyaline sphere- like aggregates. What is the most likely diagnosis? @Skleroma Adenoviral rhinitis Allergic rhinitis Rhinoviral infection Meningococcal nasopharyngitis # 51 A 22-year-old patient was admitted to the hospital with complaints of heavy nasal breathing. During the examination of her nasal cavity the doctors found thickened mucous membrane, a lot of mucus and nodular infiltrates without erosions in the nose.The nasal rhinoscleroma was diagnosed. The biopsy was taken. What typical morphological changes may be found? Granulomas with Langhan’s cells @Granulomas with Mikulicz’s cells Granulomas with Virchow’s cells Granulomas with foreign body cells Interstitial inflammation # 52 A patient, who had complains of dyspnoae, was done a biopsy of the nasal mucous membrane. The diagnosis was made – rhinoscleroma. What cells are typical for this illness? Plasmocytes Pirogov-Langhans’ cells @Mikulicz’s cells Lymphocytes Schaumann’s corpuscles # 53 At a 45-year-old man the biopsy procedure of his nasal cavity's mucosa was performed. The diagnosis of rhinoscleroma made. What cells are typical for the disease? @Mikulicz's cells Pirogovs' - Langhans' cells Plasma cells Lymphocytes Schaumann"s bodies # 54 A 40-year-old man presented with hyperemia and edema of skin in the neck region. In course of time a small abscess developed there. The focal was solid of yellow-green color. White grains could be seen in the purulent mass. Histological examination showed there druses of fungi, plasmatic and xanthoma cells, macrophages. Indicate the most possible kind of mycosis. Sporotrichosis Aspergillar Candidiasis @Actinomycosis Coccidioidomycosis # 55 A 40 year old man gained plethora and swelling on his neck. Some time after it developed into a small abscess. On incision nidus is thick, yellowish-green coloured. In purulent masses small white grains can be seen. Histologically: fungi mycelia, plasma cells, xantome cells, macrophages are revealed. What is the most probable type of mycosis? @Actinomycosis Aspergillosis Candidosis Sporotrichosis Coccidiomycosis # 56 Microscopical examination of an infiltrate removed from the submandibular skin area of a 30 y.o. man revealed foci of purulent fluxing surrounded by maturing granulations and mature connective tissue, the pus contains druses consisting of multiple short rod-like elements with one end attached to the homogenous centr E. What disease is it? @Actinomycosis Tuberculosis Syphilis Candidosis - # 57 Recovery of an organism from an infectious disease is accompanied by neutralization of antigens by specific antibodies. What cells produce them? Tissue basophils Fibroblasts @Plasmocytes T-lymphocytes Eosinophils # 58 The woman of 37 years old during one year periodically had infectious diseases of a bacterial genesis, their current was during the long term, the remissions - short-term. The hypogamaglobulinemia is found out during the inspection. Which infringement of function of the cells can be its direct reason? @Plasma cells Phagocytes Neutrophils Macrophages Lymphocytes # 59 |